Cough is one of the most common symptoms encountered in primary care in India and serves as an important protective respiratory reflex.^[1] Clinical assessment should classify cough by duration as acute (<3 weeks), subacute (3–8 weeks), or chronic (>8 weeks), and by sputum production as productive or non-productive. A focused history and examination can help identify common causes such as asthma, COPD, bronchiectasis, pneumonia, GERD, drug-induced cough, tuberculosis, and respiratory infections, while recognizing red flags suggestive of malignancy or other serious disease. Assessment may include validated cough scores, cough frequency, chest radiography for chronic cough, and CT/HRCT when indicated. Management should prioritize treatment of the underlying cause. For symptomatic relief, antitussives may be considered for troublesome nonproductive cough, while expectorants and mucolytics can assist selected patients with productive cough. CDSCO-approved combinations cited by IMA include Dextromethorphan 10 mg + Chlorpheniramine 2–4 mg/5 mL for dry cough; Bromhexine 4 mg + Guaifenesin 50 mg + Terbutaline 1.25 mg/5 mL for productive cough; and Levosalbutamol 1 mg + Ambroxol 30 mg + Guaifenesin 50 mg/5 mL for cough with bronchospasm.^[2] Symptomatic combinations should be used judiciously and generally for short-term treatment.